
( Brand: Dyadic Systems ), ( Model: SCN5-010-AS03-NA ), ( Part Type: Actuator Control Linear Drive ), ( Country/region Of Manufacture: Japan )
The SCN5-010-AS03-NA Dyadic is a high-quality, research-grade product designed for use in various scientific applications. This product is a dyadic, meaning it consists of two components that interact with each other.
The first component of the dyadic is a recombinant human Scotch type Na channel (hNav1.5) alpha subunit, specifically the SCN5A isoform. This subunit is a key component of the voltage-gated sodium channel in the heart, responsible for the rapid upstroke of the action potential, which is critical for normal cardiac function. The recombinant nature of this subunit ensures that it is free of any endogenous contaminants, making it a valuable tool for studying the function of this channel in isolation.
The second component of the dyadic is a recombinant beta-1 subunit of the human sodium channel. This subunit is essential for the proper expression and function of the sodium channel, improving channel stability and reducing channel inactivation.
The SCN5-010-AS03-NA Dyadic is produced using a stable cell line expression system, ensuring consistent quality and high-yield production. The product is purified using advanced chromatography techniques to remove any impurities, resulting in a highly pure and active sodium channel that is ideal for biochemical and electrophysiological studies.
In summary, the SCN5-010-AS03-NA Dyadic is a high-quality research tool for studying the function of the human sodium channel in cardiac cells. Its recombinant nature, combined with the inclusion of a beta-1 subunit, ensures consistent and stable channel expression, making it an invaluable resource for researchers in the fields of cardiology, electrophysiology, and molecular biology.
The SCN5A (scn5-010-as03-na Dyadic) is a research tool used in the study of ion channels, specifically the human sodium channel alpha subunit. Here are some pros and cons of purchasing this product:
Pros:1. High Purity: The SCN5A Dyadic is highly purified, ensuring that it is free from contaminants that could interfere with your experiments.
2. Consistent Quality: Dyadic expression systems are known for their ability to produce consistent results, which can be a significant advantage in scientific research.
3. Versatility: This protein can be used in a variety of studies, including ion channel function, drug discovery, and genetic diseases.
Cons:1. Expense: High-quality research tools like the SCN5A Dyadic can be expensive. This may be a consideration for researchers with limited budgets.
2. Complexity: The use of this protein requires a certain level of expertise and equipment, which may not be available to all researchers.
3. Time-Consuming: The process of expressing and purifying the protein can be time-consuming, which may delay research progress.
In conclusion, the SCN5A Dyadic is a valuable tool for researchers studying ion channels. Its high purity, consistent quality, and versatility make it an attractive option. However, its expense, complexity, and time-consuming nature are factors that should be considered before making a purchase. If a researcher has the necessary expertise, equipment, and budget, the SCN5A Dyadic can be a valuable addition to their research toolkit. If not, alternative, less expensive methods or tools may be more appropriate.
Less than 1 hour of run time on it. Comes with control cable approx 10ft. Used very briefly for an experiment. Dyadic Systems linear actuator.